http://chromatographyonline.findpharma.com/lcgc ChromatographyOnline, the website of LC/GC North America, provides applications-based technical information and practical troubleshooting advice to chromatographers and analytical chemists. 2008-09-05T22:34:18Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Aquatic-Sampling-of-Pesticide/ArticleStandard/Article/detail/547105?ref=25 Researchers from the Helmholtz Centre for Environmental Research (Leipzig, Germany) used the Chemcatcher aquatic passive sampling device to collect samples from a 1-day pulse contamination with the pesticide thiacloprid. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Scientists-Determine-Cause-of-Odors-in-Car-AC-Unit/ArticleStandard/Article/detail/547454?ref=25 Scientists from Kangwon National University in South Korea undertook a comprehensive study to identify the types of compounds in vehicle AC unit emissions, using gas chromatography with four types of detection: olfactometry, flame ionisation detection (FID), mass spectrometry (MS) and atomic emission detection (AED). It was conducted on a lab-scale model unit that contained a rogue AC evaporator from a vehicle that was associated with unpleasant odours and had only 4000 km on the clock. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Scientists-Combine-Dynamic-Liquid-Phase-Extraction/ArticleStandard/Article/detail/547484?ref=25 Two scientists based in Taiwan have combined dynamic liquid phase extraction with nanoscale volumes for GC-MS analysis, scaling down the corresponding microscale procedure to what they claim is "the smallest amount of extraction phase and sample solution in [the] GC-MS." 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/SPME-Headspace-GC-Analysis-of-BTEX-in-Waste-Treatm/ArticleStandard/Article/detail/547109?ref=25 Researchers from Sao Cristovao and Salvador, Brazil employed a solid-phase microextraction (SPME-headspace gas chromatography (GC) method to analyze benzene, toluene, ethylbenzene, and xylenes (BTEX) in water released from a waste treatment plant. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc+News/Ion-Exchange-Chromatography-Protein-Behavior/ArticleStandard/Article/detail/547063?ref=25 Scientists from Jacobs University (Bremen, Germany) used orthogonal proteomic methods to study the behavior of proteins in ion-exchange chromatography. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Analysis-of-Phenolic-Compounds-in-Water/ArticleStandard/Article/detail/547107?ref=25 Chemists from Normal University and Wuhan University (both Wuhan, China) used an improved liquid-liquid-liquid microextraction method in the analysis of four phenolic compounds in water. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Researchers-Discover-Pesticide-Build-Up-Could-Lead/ArticleStandard/Article/detail/547386?ref=25 Penn State researchers have discovered that pesticide build-up could lead to poor honey bee health. The researchers analyzed pollen, brood, adult bees, and wax samples. The results show unprecedented levels of fluvalinate and coumaphos - pesticides used in the hives to combat varroa mites - in all comb and foundation wax samples. They also found lower levels of 70 other pesticides and metabolites of those pesticides in pollen and bees. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Detecting-Nitric-Oxide-with-Capillary-Electrophore/ArticleStandard/Article/detail/547060?ref=25 Researchers from the Second Military Medical University (Shanghai, China) used capillary electrophoresis with laser-induced fluorescence detection to detect the release of nitric oxide from single neuron and mammalian cells. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Seegene-and-Shimadzu-Form-Partnership-for-Pathogen/ArticleStandard/Article/detail/547056?ref=25 Seegene, Inc. (Rockville, Maryland) and Shimadzu Corporation (Columbia, Maryland) announced that they had formed a strategic partnership to combine Seegene's Seeplex multipathogen tests with Shimadzu's MultiNA high-speed electrophoresis system. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Hyphenated/College-Unveils-New-Science-Center/ArticleStandard/Article/detail/547468?ref=25 The College of William and Mary (Williamsburg, Virginia) unveiled its Integrated Science Center for the fall semester. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/Researchers-Study-Loss-of-Vitamin-C-in-Various-Bab/ArticleStandard/Article/detail/547465?ref=25 A group of researchers at the University of Nevada-Reno (Reno, Nevada), led by Dr. Jimi Francis, conducted a study, "Comparative Analysis of Nutrients in Baby Milk Using Varied Milk Delivery Systems." The study measured the level of nutrient loss using HPLC methods during simulated baby bottle feedings and has found that some bottle types resulted in significant loss of ascorbic acid (vitamin C) during a typical 20-min feeding. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Ultrafiltration-Based-Sample-Preparation-in-Corn-C/ArticleStandard/Article/detail/547066?ref=25 Researchers from the University of Veterinary Medicine and University of Vienna (Vienna, Austria) developed a selective method for analyzing a compound in corn, deoxynivalenol, based on immuno-ultrafiltration. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Researchers-Determine-the-Smell-of-Skin-Cancer-Usi/ArticleStandard/Article/detail/547399?ref=25 Researchers from the Monell Center (Philadelphia, Pennsylvania) used GC-MS techniques to sample air above basal cell tumors and found a different profile of chemical compounds compared to the skin in healthy people. Human skin has many airborne chemical molecules known as VOCs, many of which have odors. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Mass-Spectrometry-Used-to-Identify-Proteins-in-Fos/ArticleStandard/Article/detail/547051?ref=25 Scientists from North Carolina State University (Raleigh, North Carolina) and Harvard University (Cambridge, Massachusetts) have used Thermo Fisher Scientific (San Jose, California) LTQ linear ion trap and LTQ Orbitrap XL mass spectrometers to extract and sequence tiny pieces of collagen protein from a dinosaur and a mastodon. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Thermo-Fisher-Scientific-Receives-Awards-for-Softw/ArticleStandard/Article/detail/547052?ref=25 Thermo Fisher Scientific (Waltham, Massachusetts) announced that it had received five Scientific Computing 2008 Readers’ Choice awards for software in four categories: laboratory information management systems (LIMS), bioinformatics, chromatography, and spectroscopy. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Multiresidue-Antibiotic-Analysis/ArticleStandard/Article/detail/547067?ref=25 Scientists from the USDA';s Eastern Regional Research Center (Wyndmoor, Pennsylvania) analyzed 11 beta-lactam antibiotics in bovine kidney using a sample preparation method consisting of an acetonitrile-water extraction followed by a dispersive solid-phase extraction with a C18 sorbent, extract concentration, and filtration with syringeless filter vials. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/Chromatide-and-Kromasil-Form-Research-Partnership/ArticleStandard/Article/detail/547382?ref=25 Chromatide has announced a partnership with Kromasil, a brand of Akzo Nobel, to develop improved chromatography media for chiral purification. 2008-09-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LCGC-Europe-eNews-Example/ArticleStandard/Article/detail/545202?ref=25 LCGC Europe eNews Example 2008-08-27T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LCGC-Asia-eNews-Example/ArticleStandard/Article/detail/545200?ref=25 LCGC Asia eNews Example 2008-08-27T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+LC%2FHPLC/SELS---Solvent-Enhanced-Light-Scattering/ArticleStandard/Article/detail/544881?ref=25 Viscotek has been a strong advocate of good chromatography as a prerequisite for GPC (Gel Permeation Chromatography) data accuracy. Our recent work in application development has been driven by... 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+GC/Fast-Bioethanol-Analysis-Following-ASTM-Method-D-5/ArticleStandard/Article/detail/544884?ref=25 The Zebron ZB-Bioethanol GC column reduces fuel ethanol analysis time to less than 8 min, while providing complete resolution of methanol and ethanol from all denaturant components. This newly developed GC column is suitable for... 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+LC%2FHPLC/TSK-GEL-ODS-140HTP-23-um-Ultra-High-Performance-Re/ArticleStandard/Article/detail/544883?ref=25 Short analyses time and high resolution are in great demand from R&D and QC departments within the pharmaceutical industry. Sub-two micron ODS reversed phase columns have recently been introduced to meet... 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+LC%2FHPLC/Direct-Determination-of-Cyanate-in-a-Urea-Solution/ArticleStandard/Article/detail/544880?ref=25 Urea is commonly used in protein purification, including large-scale purification of recombinant proteins for commercial purposes, and in recombinant protein manufacturing to denature and solubilize proteins (1). In aqueous solutions, urea degrades to cyanate and ammonium, with the maximum degradation rate occurring at... 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+Sample+Prep/On-Site-Sample-Preparation-Using-MEPS-for-Waste-Wa/ArticleStandard/Article/detail/544889?ref=25 MEPS uses a barrel insert and needle (BIN) device to reduce Solid-Phase Extraction (SPE) to a micro-scale suitable for small volume samples and for the online adaptation of conventional SPE techniques. Because the SPE cartridge (BIN) is incorporated into the needle assembly of a gas-tight syringe, MEPS... 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+Hyphenated/Increasing-LC-MS-MS-Sensitivity-with-Luna-HILIC/ArticleStandard/Article/detail/544885?ref=25 The analysis of polar compounds in support of clinical and preclinical pharmacokinetic studies requires an analytical methodology capable of achieving ultra-low detection and quantification limits. The high sensitivity afforded by coupling HPLC with tandem mass spectrometry (MS-MS) has made it... 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Application+Notes%3A+Pharmaceutical/Application-of-Novel-Ethylene-Bridged-Hybrid-Parti/ArticleStandard/Article/detail/544846?ref=25 Many polar compounds such as amino acids, oligonucleotides, and small molecules (i.e., metabolites) have important biological significance. Hydrophilic interaction chromatography (HILIC) is a chromatographic technique that has been used to improve the retention of very polar species that are poorly retained in reversed-phase HPLC (RP-HPLC). This is achieved by utilizing a high organic, low aqueous mobile phase in combination with a polar stationary phase. Using this chromatographic technique with highly efficient, 1.7 ?m UPLC? ethylene bridged hybrid (BEH) particles results in faster methods that exhibit improved polar retention, higher sensitivity, enhanced chromatographic resolution, and significantly improved column lifetime. 2008-08-26T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Authors-Guidelines/ArticleStandard/Article/detail/543759?ref=25 2008-08-21T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Featured+News/Torion-Technologies-Inc-Partners-with-Smiths-Detec/ArticleStandard/Article/detail/542844?ref=25 Torion Technologies Inc. (American Fork, Utah), a manufacturer of automated miniaturized, hand-portable GC and toroidal ion trap mass spectrometry (TMS) technology, has announced a partnership with Smiths Detection (Danbury, Connecticut), part of the global technology business, Smiths Group and a technology developer and manufacturer of sensors that detect and identify explosives, chemical and biological agents, weapons, and contraband. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/LEAP-Technologies-and-Quantum-Analytics-Announce-P/ArticleStandard/Article/detail/542813?ref=25 LEAP Technologies (Carrboro, North Carolina) and Quantum Analytics (Foster City, California) have announced a co-marketing partnership designed to improve chromatography and mass spectrometer systems, including new developments in front-end automation. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Protein-Isolation-Using-Multipurpose-Peptide-Tags/ArticleStandard/Article/detail/542824?ref=25 A research group at Lund University (Lund, Sweden) fused a multifunctional peptide tag to the N-terminal ends of green fluorescent protein, lactate dehydrogenase, and human hemoglobin in preparation for separation via ion-exchange chromatography, immobilized metal-ion affinity chromatography, and hydrophobic interaction chromatography. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Headspace-Sorptive-Extraction-of-Sulfur-Compounds-/ArticleStandard/Article/detail/542826?ref=25 Chemists from Wuhan University (Wuhan, China) used a headspace sorptive extraction technique based on a coated glass bar to determine volatile organic sulfur compounds in water. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Whitesides-to-Deliver-Pittcon-2009-Plenary-Lecture/ArticleStandard/Article/detail/542811?ref=25 The Pittsburgh Conference (Pittsburgh, Pennsylvania) has announced that George M. Whitesides, the Woodford L. and Ann A. Flowers University Professor of the Department of Chemistry and Chemical Biology at Harvard University (Cambridge, Massachusetts), will be the Plenary Speaker at Pittcon 2009 on March 8, 2009. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Thermo-Fisher-Scientific-Receives-Microsoft-Award/ArticleStandard/Article/detail/542809?ref=25 Thermo Fisher Scientific (Waltham, Massachusetts) has received a Microsoft Corporation 2008 Pharmaceutical and Life Sciences Innovation Award in the Discovery and Product Innovation category. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/In-Syringe-Liquid-Liquid-Microextraction-of-Drug/ArticleStandard/Article/detail/542832?ref=25 Researchers from Soochow University (Taipei, Taiwan, Republic of China) applied an in-syringe liquid-liquid microextraction technique to prepare a clenbuterol sample for analysis by high performance liquid chromatography (HPLC). 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/SPME-GC-MS-Analysis-of-VOCs-and-Disinfection-By-Pr/ArticleStandard/Article/detail/542829?ref=25 Researchers from Waterloo University (Waterloo, Ontario, Canada) developed a fast method for extracting and analyzing volatile organic compounds (VOCs) and disinfection by-products in drinking water. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Dynamic-Liquid-Phase-Extraction-of-Anti-Inflammato/ArticleStandard/Article/detail/542822?ref=25 Researchers at the University of Cordoba (Cordoba, Spain) used dynamic liquid-phase microextraction with an ionic liquid as the acceptor phase to extract six nonsteroidal anti-inflammatory drugs from human urine samples. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Shimadzu-and-Seegene-Announce-Partnership/ArticleStandard/Article/detail/542818?ref=25 Shimadzu Corporation (Columbia, Maryland) and Seegene, Inc. (Rockville, Maryland) have entered into a partnership in which Seegene's polymerase chain reaction-based Seeplex tests will be combined with Shimadzu's MultiNA high-speed electrophoresis system for multipathogen analysis and detection. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Agilent-and-University-of-Technology-Sydney-Establ/ArticleStandard/Article/detail/542816?ref=25 Agilent Technologies (Santa Clara, California) and the University of Technology Sydney (UTS, Sydney, Australia) have established the UTS Elemental Bio-Imaging Facility to study trace metals and other elements in tissue and their effects on health. 2008-08-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Overcoming-Compound-Volatility-with-Sub-ambient-EL/ArticleStandard/Article/detail/535001?ref=25 Polymer Laboratories, now a part of Varian, Inc. has published an application note on Overcoming Compound Volatility with Sub-ambient ELSD. Sub-ambient evaporative light scattering detection is valuable in the analysis of semi-volatile compounds. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Determining-Distribution-of-Erlotinib-in-Pancreati/ArticleStandard/Article/detail/542010?ref=25 Imaging Mass Spectrometry (IMS) using matrix-assisted laser desorption ionization (MALDI) is being investigated using a linear ion trap with the overall goal of analyzing the distribution of various targeted therapies within patients' tumors. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Ask-the-Editor-The-Effect-of-Sample-Diluent-Ionic-/ArticleStandard/Article/detail/535023?ref=25 What is the effect of sample diluent ionic strength? 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Isocratic-Separation-of-Acetaminophen-Phenylephrin/ArticleStandard/Article/detail/535003?ref=25 In this note, we describe an isocratic method for the simultaneous determination of the four component cold remedy that can be used for high-throughput screening. For comparison, a gradient protocol and a two-step flow gradient under isocratic conditions are also explored. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Market-Profile-Mass-Spectrometry-in-North-America-/ArticleStandard/Article/detail/535010?ref=25 Despite a recent history of major innovation in many areas of the market, the position of mass spectrometry as one of the most powerful analytical techniques available and the cutting edge applications in which it is use seem to drive on the continuation of such a rapid pace of innovation and breakthroughs. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/From-the-Editor-PharmSep-Comes-to-Philadelphia/ArticleStandard/Article/detail/535007?ref=25 In recent months, many readers have inquired about the status of "PharmSep: LCGC's Premier Symposium for Separation Scientists in Pharmaceuticals," and after some initial scheduling issues, there is good news on this front. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Employing-a-Dual-Co-Solvent-System-to-Improve-Solu/ArticleStandard/Article/detail/535004?ref=25 Whelk-O 1 is a covalently bonded chiral stationary phase known for its stability and universal solvent compatibility. Without solvent limitations, using Whelk-O 1 allows the separation scientist to optimize solubility and productivity in both analytical and preparative scale separations. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Technology-Forum-Software/ArticleStandard/Article/detail/535049?ref=25 This month E-Separations Solutions' Technology Forum looks at the topic of Software and the trends and issues surrounding it. Joining us for this discussion is Jan Hruby of DataApex, Albert Barckhoff of PerkinElmer, Bob McDowall Ph.D. of McDowall Consulting, and Ed Long, Barry Coope, and Seamus Mac Conaonaigh of Thermo Fisher Scientific, Inc. 2008-08-08T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Featured+News/LCGCs-The-Peak-Wins-ASBPE-Gold-Award-for-Second-Co/ArticleStandard/Article/detail/534314?ref=25 For the second year in a row, LCGC's digital edition, "The Peak," has won the American Society of Business Publication Editors' Gold Award for General Excellence. 2008-08-06T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Thermo-Acquires-Chemito-Technologies-Pvt-Ltd/ArticleStandard/Article/detail/533926?ref=25 Thermo Fisher Scientific Inc. (Waltham, Massachusetts), has acquired the analytical technologies and environment instrumentation divisions of Chemito Technologies Pvt. Ltd (Mumbai, India). 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Column%3A+MS+-+The+Practical+Art/A-Mass-Spectrometry-Primer-Part-I/ArticleStandard/Article/detail/542753?ref=25 Michael Balogh begins a three-part overview series, answering questions about mass spectrometers, their use and capabilities, and including links to more detailed further reading in readily available articles written for the nonspecialist. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Chemometrical-Experimental-Design-Based-Optimizati/ArticleStandard/Article/detail/542755?ref=25 A synopsis of our work detailing the use of chemometric response surface methodology (RSM) in two capillary electrophoresis (CE) studies is described. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Call-for-Papers-for-the-9th-Csaba-Horvath-Medal-Aw/ArticleStandard/Article/detail/533918?ref=25 Currently papers are being accepted for the 9th Csaba Horvath Medal Award Symposium to be held on April 28-29, 2009 at the Hartford Convention Center in Hartford, Connecticut. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Peaks+of+Interest/Researchers-Develop-New-Method-for-Drug-Testing/ArticleStandard/Article/detail/542747?ref=25 U.S. researchers have developed a new LC–MS-MS method that is more sensitive for detecting if athletes have taken drugs to artificially boost testosterone and increase physical performance. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Literature/Literature/ArticleStandard/Article/detail/542757?ref=25 PHOTONIS' "Time-of-Flight Detector Selection Guide" offers a comprehensive list of products ranging from 8 mm to 40 mm in diameter. The guide is available for free by registering on the company's website. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Calendar/Calendar/ArticleStandard/Article/detail/542758?ref=25 HUPO 7th Annual World Conference 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/Scientists-from-Taiwan-Develop-Compatible-Method-f/ArticleStandard/Article/detail/533912?ref=25 Scientists from Taiwan have developed a method for dispersive liquid-liquid microextraction of ionisable compounds that renders it compatible with reversed-phase HPLC by combining it with in-syringe back extraction. The new system was demonstrated with the removal of the drug clenbuterol from water. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Chiral-Derivatizing-Agents-Aid-Enantioseparation-o/ArticleStandard/Article/detail/533345?ref=25 Researchers at the Indian Institute of Technology Roorkee (Roorkee, India) prepared chiral dichloro- and monochloro s-triazines by nucleophilic displacement of chlorine atoms in s-triazine chloride and its 6-methoxy derivative with various amino acid amides. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Peaks+of+Interest/Phenomenex-Expands-Network/ArticleStandard/Article/detail/542749?ref=25 Phenomenex, Inc. (Torrance, California), a consumables manufacturer, has announced the opening of its new subsidiary in Utrecht, the Netherlands. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Peaks+of+Interest/Horizon-Technology-Partners-with-World-Water-Monit/ArticleStandard/Article/detail/542748?ref=25 Horizon Technology (Salem, New Hampshire), a manufacturer of automated sample preparation equipment, has announced that it has partnered with the Water Environment Federation and the International Water Association to promote World Water Monitoring Day (WWMD) 2008. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/New-Method-Developed-to-Detect-Drug-use-During-Pre/ArticleStandard/Article/detail/533914?ref=25 Italian scientists have conducted a systematic study of drug levels in the nails of newborn babies as an indicator of drug exposure during pregnancy using GC-MS. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Solid-Phase-Microextraction-Used-in-Mycotoxin-Anal/ArticleStandard/Article/detail/533342?ref=25 A research group from the University of Waterloo (Waterloo, Ontario, Canada) has used solid-phase microextraction (SPME) coupled with liquid chromatography-tandem mass spectrometry (LC-MS-MS) to determine the mycotoxin ochratoxin A in human urine. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Peaks+of+Interest/Restek-ESOP-Transition/ArticleStandard/Article/detail/542746?ref=25 Restek Corporation (Bellefonte, Pennsylvania), has announced its anticipated January 1, 2009 transition from 22% to 100% employee ownership under an ESOP structure. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/National-Institutes-of-Health-Grants-University-of/ArticleStandard/Article/detail/533373?ref=25 The National Center for Research Resources, a branch of the National Institutes of Health, has granted the University of Wisconsin- Madison a $1.6 million federal grant to purchase a mass spectrometer, a nuclear magnetic resonance spectrometer, and a liquid-chromatography system, integrated into a single instrument. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Short+Courses/Short-Courses/ArticleStandard/Article/detail/542759?ref=25 Gas Chromatography: Fundamentals, Troubleshooting, and Method Development 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Chromatography+Market+Profile/India/ArticleStandard/Article/detail/542750?ref=25 Although the Indian economy has garnered world attention with its importance in the IT and service sectors, the country recently has become far more prominent in industries that are strong sources of demand for analytical instrumentation. Foremost among these is the pharmaceutical industry, as India is now the fourth largest country in terms of production volume. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Phenomenex-Opens-Office-in-the-Netherlands/ArticleStandard/Article/detail/533336?ref=25 Phenomenex (Torrance, California), a manufacturer of separation science consumables, has announced that it has opened a subsidiary in Utrect, The Netherlands. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Ultrasound-Assisted-Extraction-of-Haloacetic-Acids/ArticleStandard/Article/detail/533344?ref=25 Chemists from the University of Cordoba (Cordoba, Spain) used a continuous ultrasound-assisted approach to extract nine haloacetic acids from vegetables and conversion to methyl esters for gas chromatography (GC) analysis. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc+News/Bruker-Daltonics-Receives-Award/ArticleStandard/Article/detail/533337?ref=25 Bruker Corporation (Billerica, Massachusetts) announced that Frost & Sullivan has selected the Bruker Daltonics CBRNE detection business for the Frost & Sullivan 2008 Technology Leadership Award in the chemical, biological, radiological, and nuclear detection markets. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Column%3A+LC+Troubleshooting/Column-Care/ArticleStandard/Article/detail/542752?ref=25 After returning from Israel, John Dolan dedicates this month's column discussion to three problems that know no international boundaries: how to condition a new column, the effect of washing a column with water, and ... 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Column%3A+Validation+Viewpoint/Linear-Thinking-in-a-Nonlinear-World/ArticleStandard/Article/detail/542754?ref=25 A very useful construct in engineering and analytical chemistry is the concept of a time-invariant linear system. The properties of the system (as for a mathematical function) are defined by a relationship between the response and the excitation, and ... 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/JASCO-and-Princeton-Chromatography-Inc-Announce-Co/ArticleStandard/Article/detail/533366?ref=25 JASCO and Princeton Chromatography have announced a collaboration in the areas of Supercritical Fluid Chromatography (SFC) instrumentation and column manufacturing. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/BTEX-in-Water-Analyzed-by-Microdrop-Extraction-and/ArticleStandard/Article/detail/533346?ref=25 Analysts from the Department of Analytical Chemistry at the University of Cordoba (Cordoba, Spain) used ionic liquid-based, single-drop microextraction followed by gas chromatography with mass spectrometric detection to analyze benzene, toluene, ethylbenzene, and xylene isomers (BTEX) in water. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Pittcon-2009-Call-for-Papers/ArticleStandard/Article/detail/533341?ref=25 The Pittsburgh Conference (Pittsburgh, Pennsylvania) has announced its Call for Papers for Pittcon 2009, the 60th annual Pittcon Conference and Exhibition to be held March 8-13, 2009 at McCormick Place South (Chicago, Illinois). 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/RTS-Life-Science-to-Host-Workshop/ArticleStandard/Article/detail/533340?ref=25 RTS Life Science (Manchester, UK), a worldwide supplier of automated sample management and drug delivery testing systems, announced that it will host a workshop at the IQPC Fourth Annual Compound Management & Integrity Conference (CMI) in Philadelphia, Pennsylvania, which is scheduled for September 22-24, 2008. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Thermo-Fisher-Scientific-Wins-Pharmaceutical-and-L/ArticleStandard/Article/detail/533339?ref=25 Thermo Fisher Scientific (Waltham, Massachusetts) announced that it is the winner of a Microsoft Corporation 2008 Pharmaceutical and Life Sciences Innovation Award in the discovery and product innovation category. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Headspace-Sampling-Used-to-Analyze-Background-Vapo/ArticleStandard/Article/detail/533343?ref=25 Researchers from Dow Chemical Company (Midland, Michigan) used headspace sampling with gas chromatography to analyze the concentration and identity of compounds in the vapor above six ionic liquids at a temperature of 100 ?C. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Column%3A+Column+Watch/Highlights-of-HPLC-2008-Part-I/ArticleStandard/Article/detail/542751?ref=25 HPLC 2008 was held in Baltimore in May. Columnist Ron Majors covers the highlights of this major symposium, held in the U.S. every two years. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/Optical-Fiber-Detector-Developed-by-Scientists-usi/ArticleStandard/Article/detail/533906?ref=25 An optical fiber detector has been developed by Portuguese scientists for the measurement of simple alcohols in industrial atmospheres following GC separation. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Departments%3A+Products/Products/ArticleStandard/Article/detail/542756?ref=25 Waters' Xevo TQ tandem quadruple mass spectrometer includes a startup feature designed to ensure that the system is ready for use by performing mass calibration, setting MS resolution, generating compound-specific MS methods (SIR or MRM), and optimizing API source conditions for specific analytical requirements. According to the company, the systems' ScanWave-enabled mode of operation utilizes a collision cell that allows scientists to easily confirm the identities and structures of targeted analytes. 2008-08-01T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Education/ArticleStandard/Article/detail/533716?ref=25 Upcoming education courses, workshops, and seminars. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Horizon-Technology-Partners-with-World-Water-Monit/ArticleStandard/Article/detail/533713?ref=25 Horizon Technology (Salem, New Hampshire), a manufacturer of automated sample preparation equipment, has announced that it has partnered with the Water Environment Federation and the International Water Association to promote World Water Monitoring Day (WWMD) 2008. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/From-the-Editor-PharmSep-Comes-to-Philadelphia/ArticleStandard/Article/detail/533707?ref=25 In recent months, many readers have inquired about the status of "PharmSep: LCGC's Premier Symposium for Separation Scientists in Pharmaceuticals," and after some initial scheduling issues, there is good news on this front. I am pleased to announce that this event has officially been rescheduled and is ready to kickoff later this year, from September 9-11, in Philadelphia, Pennsylvania. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Events/ArticleStandard/Article/detail/533715?ref=25 Upcoming events 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Researchers-Develop-New-Method-for-Drug-Testing/ArticleStandard/Article/detail/533712?ref=25 U.S. researchers have developed a new LC-MS-MS method that is more sensitive for detecting if athletes have taken drugs to artificially boost testosterone and increase physical performance. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Evaluation-of-Nonpolar-Reversed-Phase-Columns-Unde/ArticleStandard/Article/detail/533698?ref=25 Supercritical fluid chromatography or subcritical fluid chromatography (SFC) is considered a normal-phase technique. In this article, we sought to examine whether it was feasible to use nonpolar columns (for example, C18) under SFC conditions to separate compounds that closely eluted or co-eluted by gradient and isocratic reversed-phase high performance liquid chromatography (HPLC). 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Enhancing-GC-MS-Analysis-of-Trace-Compounds-Using-/ArticleStandard/Article/detail/533702?ref=25 The advantages of mass spectrometry (MS) in combination with gas chromatography (GC), in terms of providing both qualitative and quantitative information, are well known. However, reliable identification and accurate measurement of trace toxic and odorous species at the lowest levels of interest can be compromised by chromatographic anomalies such as column bleed, extended solvent tails, air and water interference, and unresolved sample matrix components. To address this issue, a new software algorithm has been developed for reprocessing stored GC-MS data. It uses an innovative dynamic approach to distinguish and eliminate background interference as it changes throughout a run. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Restek-ESOP-Transition/ArticleStandard/Article/detail/533710?ref=25 Restek Corporation (Bellefonte, Pennsylvania), has announced its anticipated January 1, 2009 transition from 22% to 100% employee ownership under an ESOP structure. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Phenomenex-Expands-Network/ArticleStandard/Article/detail/533714?ref=25 Phenomenex Inc. (Torrance, California), a consumables manufacturer, has announced the opening of its new subsidiary in Utrecht, the Netherlands. 2008-07-31T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Mass-Spectrometry-Test-for-Sports-Doping/ArticleStandard/Article/detail/530092?ref=25 Researchers at the University of Utah's (Salt Lake City) Sports Medicine Research and Testing Laboratory developed a test for testosterone and epitestosterone in urine that uses liquid chromatography with tandem mass spectrometry detection (LC-MS-MS). 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Pressurized-Liquid-Extraction-of-Amines-in-Meat/ArticleStandard/Article/detail/530103?ref=25 Researchers from the University of Barcelona (Barcelona, Spain) analyzed heterocyclic amines in meat samples using pressurized liquid extraction followed by liquid chromatography with tandem mass spectrometry detection (LC?MS-MS). 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Hyphenated/FEI-Signs-Shimadzu-for-Japanese-Distribution/ArticleStandard/Article/detail/530190?ref=25 FEI Co. ( Hillsboro, Oregon), a manufacturer of high-resolution imaging and analysis technology, has signed Shimadzu Corp (Kyoto, Japan), a leading provider of analytical instrumentation, as its sales agent in Japan. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/GC-Method-Helps-Narrow-Source-of-Drug-Distribution/ArticleStandard/Article/detail/530194?ref=25 Scientists at the National Police Scientific Institute in Ecully, France have been analyzing solvents trapped within crystals of cocaine hydrochloride with a static headspace-gas chromatography method. This method helps them ascertain the drug's country of origion, which can help determine the distribution chain. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/Wyatt-Technology-to-Host-FFF-MALS-Meeting/ArticleStandard/Article/detail/530094?ref=25 Wyatt Technology (Santa Barbara, California) has announced that it will be hosting a field flow fractionation-multiangle light scattering (FFF-MALS) meeting on October 22, 2008, at the Bacara Resort and Spa in Santa Barbara. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC/The-University-of-Technology-Jamaica-Receives-Mult/ArticleStandard/Article/detail/530171?ref=25 The University of Technology (St. Andrew, Jamaica) has received a multi-million dollar donation of lab equipment from Johnson & Johnson (Canada). 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/GC+News/Verdure-Technologies-Inc-Moves-into-New-Idaho-Head/ArticleStandard/Article/detail/530121?ref=25 Verdure Technologies, Inc., an Idaho based biotech green technologies company, moved into its new research and development facility in Pocatello Idaho. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Online+Only/Micelle-Mediated-Extraction-Used-in-Analysis-of-He/ArticleStandard/Article/detail/530105?ref=25 Researchers from Fourth Military Medical University (Shanxi, China) have developed a method for separating and determining hydrophobic compounds in Cnidium monnieri, an herbal remedy. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Online+Only/Horizon-Technology-Partners-with-World-Water-Monit/ArticleStandard/Article/detail/530104?ref=25 Horizon Technology (Salem, New Hampshire), a manufacturer of automated sample preparation equipment, has announced that it has partnered with the Water Environment Federation and the International Water Association to promote World Water Monitoring Day (WWMD) 2008. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/HPLC-Company-Folds/ArticleStandard/Article/detail/530187?ref=25 Nanostream, Inc. (Pasadena, California), a developer of microfluidics-based parallel HPLC technology and a provider of assay development has closed all business operations. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Sample+Prep/Electromembrane-Peptide-Extraction/ArticleStandard/Article/detail/530102?ref=25 A research group at the University of Oslo (Oslo, Norway) developed a method for electromembrane extraction of eight peptides from an aqueous acidic solution using a thin supported liquid membrane in a porous hollow fiber. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/LC%2FHPLC/Advanced-Materials-Technology-and-Capsulution-Nano/ArticleStandard/Article/detail/530125?ref=25 Advanced Materials Technology (Wilmington, Delaware), a manufacturer and developer of columns for HPLC, and the Berlin-based Capsulution NanoScience AG signed a license contract for the use of the LBL? Technology in June. 2008-07-15T04:00:00Z http://chromatographyonline.findpharma.com/lcgc/Misc/JEOL-Receives-Award-for-Customer-Service/ArticleStandard/Article/detail/530091?ref=25 JEOL USA (Peabody, Massachusetts) has received an award for excellence in customer satisfaction as judged by its customers. 2008-07-15T04:00:00Z